The notion of subtyping has gained an important role both in theoretical and applicative domains: in lambda and concurrent calculi as well as in programming languages.The soundness and the completeness, together referred Gua Sha to as the preciseness of subtyping, can be considered from two different points of view: operational and denotational.The
Single-Domain Antibodies and Their Formatting to Combat Viral Infections
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as Nanobodies®, have changed the landscape of affinity reagents.The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of production and formatting flexibility favor VHHs over conventional antibody formats for many applica
Second opinions in medical oncology
Abstract Background The current study aimed to further our understanding of second opinions among medical oncology patients by examining the proportion of patients who sought a second opinion about their cancer treatment, and why.Methods The study was conducted between 2013 and 2015 in three medical oncology clinics located in public hospitals in A
Intending the Unintended: The Act of Building Agent-based Models as a Regular Source of Knowledge Generation
Poverty is a complex issue that is rarely conducive to analysis in laboratory or field experiments.Effective interventions that aim to decrease or eliminate poverty require an understanding of the intricate web of associated social issues.The need for this increased comprehension necessitates the use of alternative robust means of analysis: one suc